Characterization of Microparticles for Lung Cancer Delivery

Категория: Онкология. Опухоли

Characterization of Microparticles for Lung Cancer Delivery
Characterization of Microparticles for Lung Cancer Delivery
Автор
Год выпуска
2013
Издательство
LAP Lambert Academic Publishing
Страниц
60
Наличие
товар закончился
Drug delivery through the use of hydrogel biomaterials has received a considerable amount of progress over the past decade especially for pharmacological purposes like lung cancer treatment. However, substantial challenges for effective treatment remain including targeting and controlled release. The design of the human lung provides a unique filter system that allows large particles in the venous blood stream to get trapped in the proximal capillary beds. Gel microparticles designed for the delivery of therapeutic drugs through this mechanism in the lungs are formed through a Michael-Addition reaction using polyethylene glycol (PEG) and dithiothereitol. In this book, we investigate the characteristics of PEG based hydrogels by varying the PEG concentration and molecular weight of the polymer in order to define a relationship between the rate of degradation and the crosslink density within the gel.
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Реферат
19 стр. / 1500 руб.
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